Tuesday's top stories:
- Galatasaray take a lead into the second leg at Anfield, after beating Liverpool 1-0 in a chaotic clash, where Mario Lemina's first-half header was the difference.
- Atalanta and Bayern Munich will do battle in Bergamo, in the first-ever competitive meeting between the two sides.
- Over in Madrid, Atletico will play host to Tottenham, who may be fighting a relegation battle domestically but have been a formidable opponent in Europe this season.
- Newcastle will welcome Barcelona to St. James Park for the second time this season, with the aim of avenging the narrow 2-1 defeat they suffered in September. Check out our preview of that clash here.
Tuesday's schedule:
Atalanta vs Bayern Munich - 21:00 CET
Atletico Madrid vs Tottenham - 21:00 CET
Newcastle vs Barcelona - 21:00 CET
Key updates and insights:
21:00 CET - Underway across Europe, in our three later games. What is in store for us?
20:45 CET - One final piece of team news before kick-off in 15 minutes, where the juggernaut of Bayern Munich head to Atalanta for their last 16 clash.
Despite a season of records, Harry Kane is on the bench for Bayern tonight, with Nicolas Jackson preferred for the starting berth.
Kamaldeen Sulemana gets a rare start for the hosts as he plays in a front three alongside Krstovic and Gianluca Scamacca.
20:40 CET - Advantage Galatasaray! They have beaten Liverpool 1-0 in Istanbul thanks to a seventh-minute goal from Mario Lemina.
In truth, both teams should have scored more, with the hosts shading the xG at 1.46, but Liverpool had more shots on target.
A truly chaotic clash - expect more of the same next week...
20:20 CET - More controversy at Rams Park, as Liverpool get the ball in the net from a corner, but VAR intervenes to rule it out for a handball on Ibrahima Konate - the trouble is following him around at the moment.
Meanwhile, Tottenham can park their dreadful Premier League form tonight as they travel to the Spanish capital to take on Atletico Madrid.
The big news is the omission of Vicario from the starting lineup. Igor Tudor has plumped for Antonin Kinsky to give him more security in goal, whilst former Atleti player Conor Gallagher is only on the bench.
Diego Simeone has decided to go with Antoine Griezmann to partner Julian Alvarez up top instead of Alexander Sorloth.
20:15 CET - As the chaos continues in Istanbul, let's bring you some team news from the 21:00 CET games.
Newcastle host Barcelona at St James' Park, looking to rally after a poor performance in the FA Cup at the weekend, as they were soundly beaten by Manchester City.
Eddie Howe surprisingly continues with William Osula up front, whilst there is no place in the starting line-up for Nick Woltemade.
For Hansi Flick, Robert Lewandowski is back in the XI, whilst he will be ably supported by Lamine Yamal and Raphinha.
20:06 CET - Ibrahima Konate has got out of jail thanks to the assistant referee. The French defender misjudges a backpass, and as the shot comes in past Giorgi Mamardashvili, Konate fluffs the clearance to allow Victor Osimhen tap in.
But, in the build-up, Baris Yilmaz is judged to be active, and it won't count. A huge let-off for Liverpool and Konate.
19:36 CET - The half-time whistle has blown, and Liverpool will be mighty relieved to hear it, with the hosts creating numerous openings; they could quite easily be further ahead.
The Turkish side have had nine efforts to Liverpool's three and have racked up an xG of 1.14.
Perhaps the standout performer thus far has been Gala number 10 Gabriel Sara. The Brazilian has already created four chances, more than any other player.
19:02 CET - It's been a thrilling opening quarter-hour at Rams Park, with Mario Lemina heading Galatasaray into an early lead against Liverpool.
Victor Osimhen and Florian Wirtz have also seen decent openings go to waste.
17:53 CET - The starting lineups are in from Istanbul, and the major piece of team news is that Florian Wirtz returns to the Liverpool side, with Cody Gakpo dropping to the bench.
As expected, Giorgi Mamardashvili starts in the absence of Alisson Becker, while Joe Gomez is preferred at right-back to Jeremie Frimpong.
For Galatasaray, Noa Lang starts ahead of Leroy Sane, with Ilkay Gundogan, Sacha Boey and Mauro Icardi also among the substitutes.
17:00 CET - Hello and welcome to Flashscore's coverage of the first night of 2025/26 Champions League last-16 action!
We'll be bringing you team news, live scores and in-depth insights for each of the games, so don't go anywhere.
First up tonight is Galatasaray vs Liverpool at 18:45 CET, a match-up that has historically not gone well for the Reds, and you'll be able to find the starting XIs right here as soon as they come in.