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These days, Champions League games don’t come much bigger and better than PSG versus Barcelona… that’s the undoubted highlight of Round 3.
But Bayern vs Arsenal is a tasty appetizer as well, while matchups like Real Madrid vs RB Leipzig, Liverpool vs Villarreal and FC Porto vs PSV also catch the eye.
Let us guide you through the midweek action, with insight and betting tips that you can back via an account with either FanDuel or BetMGM.
PSG vs Barcelona, Tuesday (14:00 ET)
PSG, one of the best teams to watch on the planet, has an ability to instigate chaos on the field.
The club beat Manchester City 4-2 just a short while ago, while its 2025/26 Champions League season saw 32 goals scored in just eight league phase games. Knockout stage results, beating Chelsea 5-2 and Bayern Munich 5-4, only furthered that chaos theory.
The French champions are notoriously fast starters, scoring three first-half goals in each of their two Champions League games thus far, and the signs are there that they will find the net in the first half against a Barcelona team that has kept just one clean sheet in its last five games.
Pick: PSG to Score over 0.5 in the First Half @ -198 (FanDuel) | -190 (BetMGM)
Explanation: Our bet wins if PSG scores in the first half.
Liverpool vs Villarreal, Tuesday (14:00 ET)
There may be questions for Liverpool to answer defensively.
The Reds allowed three goals against Manchester City and the same number against LASK in their last Champions League game. Doubts have been raised about some of Virgil van Dijk’s waning attributes, while his center back partner Jérémy Jacquet is very talented, but still learning his craft all the same.
But Villarreal struggles against English opposition in Europe. In its last 16 Champions League games against English clubs, it hasn’t won once, losing 10 and drawing six.
More worrying for the Spanish club, it has scored only five times in those 16 games and has lost the last nine in a row.
And while Liverpool aren't in the most sparkling of form in the league, they've looked better in this competition, seeing off Atletico Madrid 2-1 at Anfield already.
The stats point toward a Liverpool win here.
Pick: Liverpool to win @ -240 (FanDuel) | -200 (BetMGM)
Explanation: Our bet wins if Liverpool wins the match by any score.
Napoli vs Bodo/Glimt, Tuesday (14:00 ET)
Bodø/Glimt showed it’s no pushover in last season’s Champions League, claiming nine points from its eight league phase games.
The Norwegian club defeated Borussia Dortmund last time out in this competition too, but there’s a feeling that its success is partly owed to its proximity to the Arctic Circle, not an environment that visiting players are always particularly fond of.
That advantage is lost on the road, and the Norwegians can expect a hot reception from the ever-passionate Naples fans.
Napoli lost just twice in 19 home Serie A games last season and held Arsenal scoreless at Stadio Diego Armando Maradona for 75 minutes just a few weeks ago.
And while it has lost its last two home games in the UEFA Champions League, it has never previously suffered three consecutive home losses in major European competition.
Pick: Napoli to Win @ -190 (FanDuel) | -165 (BetMGM)
Explanation: Our bet wins if Napoli wins the game by any score.
Stuttgart vs Atletico Madrid, Tuesday (14:00 ET)
Stuttgart has won both of its Champions League games, but Slovan Bratislava and Viking, no disrespect, are perhaps not the best barometers of form as opponents.
Instead, we know the team has lost three of five in the Bundesliga this season, including a 5-1 thrashing at Bayern, so perhaps Stuttgart is susceptible to elite opposition.
Atlético Madrid can be placed in that category, and this Draw No Bet selection adds the safety net of the draw to our bet as well. Stuttgart is, after all, winless in seven games against Spanish clubs in the UEFA Champions League, losing five of those.
Pick: Atletico Draw No Bet @ -164 (FanDuel) | -175 (BetMGM)
Explanation: Our bet wins if Atlético wins. Our wager is refunded if the game ends in a draw.
Como vs Manchester United, Wednesday (11:45 ET)
These are troubled times at Manchester United, with its players speaking out against board-level mediocrity and talk of locker room unrest.
That will be music to the ears of Como, which has been made the favorite for this game. But how bullish can we be about a team that is new to life in the Champions League and has been in mixed form of its own lately?
Not massively, if much is read into history. Manchester United, you see, is unbeaten in its last six road games against Italian clubs in the UEFA Champions League, last losing in this competition on Italian soil in 2007.
Despite its faults, United has the attacking talent to win, or avoid defeat, against this level of opposition.
Pick: Man Utd/Draw Double Chance @ -165 (FanDuel) | -165 (BetMGM)
Explanation: Our bet wins if Manchester United wins or draws this match.
Bayern Munich vs Arsenal, Wednesday (14:00 ET)
Bayern Munich has an outstanding record against Arsenal in the Champions League (5 wins, 1 draw, 1 loss), but the Gunners seemed to break that spell in their last meeting back in November.
They won 3-1, while Bayern’s numbers (eight shots, 14 touches in the opposing penalty area, and an xG of 0.65) were its lowest in a Champions League game under head coach Vincent Kompany.
Plus, while Bayern still has an array of stars, it will be without the suspended Michael Olise for this match.
Does Arsenal head coach Mikel Arteta have Kompany’s number, tactically speaking?
Pick: Arsenal/Draw Double Chance @ -150 (FanDuel) | -155 (BetMGM)
Explanation: Our bet wins if Arsenal wins or draws this game.
Real Madrid vs RB Leipzig, Wednesday (14:00 ET)
Although Real Madrid is winning games under head coach José Mourinho, it is frequently doing things the hard way. Against Roma last time out in the Champions League, it was down 3-1 with seven minutes to play and won 4-3.
But winning breeds confidence and momentum, and this is a Real Madrid team that has scored in each of its last 44 home games in the Champions League.
We don’t expect that run to end against an RB Leipzig team whose Champions League record (2 wins, 1 draw, 9 losses) reveals its struggles in this competition.
Pick: Real Madrid -1 Handicap @ -150 (FanDuel) | -146 (BetMGM)
Explanation: Our bet wins if Real Madrid win by two or more goals.
Sporting vs LASK, Wednesday (14:00 ET)
Sporting was a seeded playoff team in last season’s Champions League, losing by a single goal to Arsenal in the quarterfinals.
It has started well this season, and we expect it to have too much firepower at home against LASK, which allowed six against Liverpool last time out. In fact, LASK has lost its last eight road games in major European competition, allowing 23 goals and scoring only three times.
Tip: Sporting -1 Handicap @ -160 (FanDuel) | -165 (BetMGM)
Explanation: Our bet wins if Sporting wins by two or more goals.
These odds, correct at the time of publication, are subject to change.