Ryan Sessegnon is leaving, with Spurs confirming the departures of Eric Dier (Bayern Munich), Ivan Perisic (Hajduk Split) and Japhet Tanganga (Millwall).
Sessegnon is leaving with a year to run on his contract.
Under-21 pair Charlie Sayers and Billy Heaps are being allowed to come off contract.
Meanwhile, under-18 players Kieran Morgan and Han Willhoft-King have also departed.