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Ipswich Town are the visitors to Manchester City, while the Cityzens’ title rivals Arsenal make the trip to Nottingham Forest.
Everton and Chelsea kick off the weekend at Goodison Park, while a feisty Yorkshire-Lancashire battle awaits at Elland Road as Leeds United offer a red-hot welcome to struggling Manchester United.
Let us guide you through the weekend’s action, with insight and betting picks that you can back through an account with Bet MGM and FanDuel.
Everton vs Chelsea, Saturday (06:30 AM ET)
Morgan Rogers, and João Pedro helping Chelsea score 15 goals thus far. That’s the third-best total in the Premier League, and just one behind current league leaders Manchester City.
Everton is one of just three teams in the Premier League that remain unbeaten. The Toffees are solid defensively but somewhat vulnerable against teams with a clear attacking plan, as both Manchester United and Hull have scored twice against them recently.
That said, Everton creates plenty of chances. And while they’re not the most prolific in front of goal, Chelsea’s generous defending should give Everton more opportunities to find the net at home.
Pick: Both Teams to Score @ -192 (FanDuel) | -185 (BetMGM)
Explanation: Our bet lands if both Everton and Chelsea score.
Brentford vs Liverpool, Saturday (09:00 ET)
They may not be the most fashionable of clubs, but write Brentford off at your peril.
The Bees were unbeaten in both of their games against Liverpool last season (1 win, 1 draw), and they haven’t lost in their last eight Premier League games, six of them coming this season.
Intriguingly, Brentford is Liverpool head coach Andoni Iraola’s “worst opponent.” As Bournemouth’s head coach, he picked up just two points in six games against them, and he has yet to crack the code.
Factor in Liverpool’s Champions League game on Wednesday, while Brentford has had the full week to prepare, and backing the Bees feels like the smart play.
Pick: Brentford/Draw Double Chance @ -250 (FanDuel) | -225 (BetMGM)
Explanation: Our bet wins if Brentford win or draw. If they lose, so does our bet.
Manchester City vs Ipswich Town, Saturday (09:00 ET)
After riding out the early storm against Liverpool at Anfield on Sunday, Manchester City’s class told in a 3-0 win.
It’s telling that City can bring players of Jérémy Doku’s level off the bench. His late cameo, which included a goal and an assist, was crucial to the victory.
Ipswich has done little wrong so far this season and currently sits tenth in the standings thanks to wins over Sunderland, Crystal Palace, and Fulham in an opening six games that also included matchups with Liverpool and Manchester United.
But City’s extraordinary record against promoted teams (28 wins, 3 draws, 0 losses) helps focus the minds of bettors.
Off-field matters (they’re contesting the guilty verdicts on 114 financial misplay charges) have galvanized Manchester City, so expect them to show their class on Saturday.
Pick: Manchester City -1 Handicap @ -196 (FanDuel) | -175 (BetMGM)
Explanation: Our bet wins if Man City win this game by two goals or more.
Brighton vs Crystal Palace, Sunday (08:00 ET)
It’s impossible not to be impressed by Brighton, whose 3-0 demolition of champions Arsenal headlines its fantastic start to the season.
The Seagulls are notoriously fast starters: they have collected 13 or more points in their opening six games for the fourth time in six seasons. Only Arsenal and Manchester City can match that record.
Crystal Palace, meanwhile, has faced more shots than any other Premier League team this season, and it has failed to score in four of its last six road games in the Premier League.
All the signs point toward a positive result for Brighton on Sunday.
Pick: Brighton to Win @ -210 (FanDuel) | -175 (BetMGM)
Explanation: Our bet wins if Brighton wins this game.
Leeds United vs Manchester United, Sunday (08:00 ET)
Elland Road will be rocking on Sunday – the last thing Manchester United, low on confidence, need.
Leeds had the luxury of a full week to prepare for this game, while the Red Devils had another bad day at the office in midweek – losing 0-2 to Atletico Madrid in the Champions League.
The Yorkshiremen are unbeaten in their last seven Premier League home games (W4 D3) too, while Man Utd have claimed just six points in as many outings this term.
Pick: Leeds/Draw Double Chance @ -250 (FanDuel) | -225 (BetMGM)
Explanation: Our bet wins if Leeds win or the game ends in a draw.
These odds, correct at the time of publication, are subject to change.